Abiogenesis and natural selection algorithms

Since its inception, the Earth has represented a sultry and hot sphere without life. After 4.5 billion years, the fauna and flora were represented by numerous forms of living organisms, continuing to evolve at the molecular level. In this work, we will try to penetrate the tectonic plates of history, layer by layer we will delve into the description of the initial algorithms of chemical reactions and answer the question: “Where, in what quantity and from what did the complex organic molecules that have come a long way of evolution into living beings? ". To curb the order of evolutionary selection will require a solid foundation of theory to further the logistics of reasoning and statistical description.

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Prologue: structure and organization of media

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1 — : « . »;

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3 — KhanAcademy: «. »;

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5 — Organic compound synthesis on the primitive earth // Science — July 1959: vol. 130, no. 3370;

6 — KhanAcademy: «»;

7 — : « . »;

8 — A semi-synthetic organism with an expanded genetic alphabet // Nature, 2014, advance online publication;

9 — Physico-chemical and evolutionary constraints for the formation and selection of first biopolymers: towards the consensus paradigm of the abiogenic origin of life // Chemistry & Biodiversity, 2007, vol. 4;

10 — α-Hydroxy and α-Amino Acids Under Possible Hadean, Volcanic Origin-of-Life Conditions // Science — October 2006: vol. 314, no. 5799;

11 — On the origin of life in the zinc world: 1. Photosynthesizing, porous edifices built of hydrothermally precipitated zinc sulfide as cradles of life on Earth // Biol. Direct, 4 (2009);

12 — An Origin-of-Life Reactor to Simulate Alkaline Hydrothermal Vents // J. Mol. Evol., 79, (2014);

13 — On the origin of life in the zinc world. 2. Validation of the hypothesis on the photosynthesizing zinc sulfide edifices as cradles of life on Earth // Biol. Direct, 4 (2009);

14 — KhanAcademy: «»;

15 — Origin of first cells at terrestrial, anoxic geothermal fields // Proc. Natl. Acad. Sci., 109 (2012);

16 — Lost City ;

17 — : « »;

18 — : « »;

19 — : « »;

20 — Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions // Nature — May 2009: vol. 459;

21 — : « »;

22 — : « »;

23 — : « »;

24 — The origin of viruses // Research in Microbiology, 2009, vol. 160;

25 — The two ages of the RNA world, and the transition to the DNA world: a story of viruses and cells // Biochimie, 2005, vol. 87;

26 — : « : - »;

27 — KhanAcademy: « »;

28 — : « »;

29 — KhanAcademy: «»;

30 — : « . »;

31 — KhanAcademy: « »;

32 — - // , 2015. . 80. . 5;

33 — KhanAcademy: « »;

34 — Complex archaea that bridge the gap between prokaryotes and eukaryotes // Nature advance online publication (2015);

35 — Asgard archaea illuminate the origin of eukaryotic cellular complexity // Nature, advance online publication (2017);

36 - KhanAcademy: Life on Earth and in the Universe section.