Sleep and life expectancy. A sleep deprivation pandemic

About times, about morals.



The world is experiencing a covid pandemic, scientists are trying to invent a vaccine in a short time to save as many people as possible. But have you ever wondered how a seemingly banal lack of sleep affects life?



He will not become the obvious cause of death of a person, because everyone sets priorities and decides whether to sleep or not. Lack of healthy sleep imperceptibly undermines internal resources: it affects the perception of the world, interferes with recovery processes and literally clutters our brain.



"I wish I didn't sleep at all, I would have time to do so many things!" - probably, almost everyone dreamed so.



There are those who treat sleep with disdain: "I'll go to bed later today, at 3 am." It doesn't matter if the person still has unfinished business or he decided to watch the series - this is repeated from day to day. And to get up, as always, by the alarm clock at 7:00. Someone is even proud of how little he sleeps. Would you think of a lack of sleep?



Is there any reason for pride? Rather the opposite.



Today the Lifext team will reveal:





image





:



, .



, , . . « », . , , , ?



: , . .



, : — .



— . 70 . .



: , , , ? «» ? , .



. , : . , 1937 : . . , .



, , , . « »: . , , .



image





, .



1949 , , . : , : . , . , , , / .



20- , . , . ? .



1926 .. .. , 50 . 1953 .



— , . , : , , . . , REM .



, , 33 , . , 90-100 . . , .



, , , . , . , , , .[1]



image







?



? ? , ! ? :





, . ? , , .





, «» , . , , , . — .





. , - — , . .



. , , . , . , . : , , . .



image



-





, . , , , , . , . [2]





, . : . , . , , , . [3]



: , . - . , , . ? , . .





.



, ! , , . 2- . : . . [4]





— , , . . .[5]



-



. : [6], . [7]. , .



image

, :)







, . . ? , . , . — .



: , . , . .[8]



, - . . , , "", . , . . , .



- , , . « » 47% - .



, , , .[9]



, , . . « ».







, 1,5-2 4-6 , 7-9 . :



— /N1 non-REM sleep



, . , 5 15 . , , . , . «», «». . . , — , .



— /N2 non-REM sleep



10 25 . , , . , : , , .. 55% .



— /N3 non-REM sleep



, , -.



, . , . .



, N3 20 40 . «» , , . , 30 , . , .



, , . .



. . , , . , , : - . [10]



— /REM sleep



. , , . , . - . , , - . . — .



:

? , , . . . , , ? ! . : 2,3,2 , 2,3 2, . .

image

,



.



, . , ? . . , . . , ? ? , ? ́ ? .



, : - 18- . . , , . « » . 24 11 [11]. , , . , . — .



— , 20 000 . , , . , , — , . , . , , , « ». 2 .



. , , . . — .[12] , . , . , ? !



! , ?



, ? , . , . . . , , — . , ?



— , . , , - . , , . , . [13] , , . ? , . , 3500 ( , ), , . ! .



? .



image





?



. 23:00 7:00, , 40% , . . , .[14] . , .



« » — , — « ». . - . 1% , — , .



. -. , 12 ? . 21 ? ! 9 ? -, : .



, . . , 5-6 , 4 . , . , . , , , — , . [15]



: , , . , 00:00.



image





?



, ? ? :





, . , , 2019 , .[16]





. , . , , 5 , , . [17] , . . [18] 150 . , : , , , , . , . 2 . ? , , . Lifext .





, . , .



. . « », «» . , 20:00 6:00. , Flux Twilight.



, . «» «». , , 3500 . : . , , « ».



? , . : , , , . ! , .



, . , !



, , . , .

image

,



, , ? , . . .[19]



?



, . . , ? ! [20] . . , . « », .



. — . , . " ".



— . , , .. , , . , "" .





, . , 3-4 , . . , . .



. . , . , , . , .[21] . — , .



— . , . -, . . -, , , . , , «» , .[22] - . -, . , , . .



:)





, , . , . , ( , , !), . — . , . . — . , . . , , ? . . .





: .



. . , ? 17-19 . , . . . , , .



— . , . 40% . , . , , . .



— 40 60%. , .





Lifext



  • — . . , , . , , .



  • /. , . . .





10 :



  • ;
  • ;
  • , ;
  • ;
  • ;
  • ;
  • ;
  • ;
  • ;
  • ;


image





, . , , " ". , , , . , :)



*[1] , «» №3, 2014,

[2]Pires GN, Bezerra AG, Tufik S, Andersen ML. Effects of acute sleep deprivation on state anxiety levels: a systematic review and meta-analysis. Sleep Med. 2016;24:109-118. doi:10.1016/j.sleep.2016.07.019

[3]Taheri S, Lin L, Austin D, Young T, Mignot E. Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med. 2004;1(3):e62. doi:10.1371/journal.pmed.0010062

[4]Mesarwi O, Polak J, Jun J, Polotsky VY. Sleep disorders and the development of insulin resistance and obesity. Endocrinol Metab Clin North Am. 2013;42(3):617-634. doi:10.1016/j.ecl.2013.05.001

[5]Mullington JM, Simpson NS, Meier-Ewert HK, Haack M. Sleep loss and inflammation. Best Pract Res Clin Endocrinol Metab. 2010;24(5):775-784. doi:10.1016/j.beem.2010.08.014

[6]Doyle CY, Ruiz JM, Taylor DJ, et al. Associations Between Objective Sleep and Ambulatory Blood Pressure in a Community Sample. Psychosom Med. 2019;81(6):545-556. doi:10.1097/PSY.0000000000000711

[7]Aziz M, Ali SS, Das S, et al. Association of Subjective and Objective Sleep Duration as well as Sleep Quality with Non-Invasive Markers of Sub-Clinical Cardiovascular Disease (CVD): A Systematic Review. J Atheroscler Thromb. 2017;24(3):208-226. doi:10.5551/jat.36194

[8]Scullin MK, Bliwise DL. Sleep, cognition, and normal aging: integrating a half century of multidisciplinary research. Perspect Psychol Sci. 2015;10(1):97-137. doi:10.1177/1745691614556680

[9]Lovato N, Lack L. Insomnia and mortality: A meta-analysis. Sleep Med Rev. 2019;43:71-83. doi:10.1016/j.smrv.2018.10.004

[10] Mander BA, Marks SM, Vogel JW, et al. β-amyloid disrupts human NREM slow waves and related hippocampus-dependent memory consolidation. Nat Neurosci. 2015;18(7):1051-1057. doi:10.1038/nn.4035

[11] William J. Cromie Gazette Staff Human Biological Clock Set Back an Hour

[12]MetaCyc Pathway: serotonin and melatonin biosynthesis

[13]Heo JY, Kim K, Fava M, et al. Effects of smartphone use with and without blue light at night in healthy adults: A randomized, double-blind, cross-over, placebo-controlled comparison. J Psychiatr Res. 2017;87:61-70. doi:10.1016/j.jpsychires.2016.12.010

[14]Kalmbach DA, Schneider LD, Cheung J, et al. Genetic Basis of Chronotype in Humans: Insights From Three Landmark GWAS. Sleep. 2017;40(2):zsw048. doi:10.1093/sleep/zsw048

[15]Minges KE, Redeker NS. Delayed school start times and adolescent sleep: A systematic review of the experimental evidence. Sleep Med Rev. 2016;28:86-95. doi:10.1016/j.smrv.2015.06.002

[16]Rusch HL, Rosario M, Levison LM, et al. The effect of mindfulness meditation on sleep quality: a systematic review and meta-analysis of randomized controlled trials. Ann N Y Acad Sci. 2019;1445(1):5-16. doi:10.1111/nyas.13996

[17]Hartescu I, Morgan K, Stevinson CD. Increased physical activity improves sleep and mood outcomes in inactive people with insomnia: a randomized controlled trial. J Sleep Res. 2015;24(5):526-534. doi:10.1111/jsr.12297

[18]Physical Activity and Adults. Recommended levels of physical activity for adults aged 18 — 64 years.

[19]Guski R, Schreckenberg D, Schuemer R. WHO Environmental Noise Guidelines for the European Region: A Systematic Review on Environmental Noise and Annoyance. Int J Environ Res Public Health. 2017;14(12):1539. Published 2017 Dec 8. doi:10.3390/ijerph14121539

[20]Locihová H, Axmann K, Padyšáková H, Fejfar J. Effect of the use of earplugs and eye mask on the quality of sleep in intensive care patients: a systematic review. J Sleep Res. 2018;27(3):e12607. doi:10.1111/jsr.12607

[21]López-Cruz L, Salamone JD, Correa M. . . 2018; 9: 526. 1 2018 . Doi: 10.3389 / fphar.2018.00526

[22]Ebrahim IO, Shapiro CM, Williams AJ, Fenwick PB. Alcohol and sleep I: effects on normal sleep. Alcohol Clin Exp Res. 2013;37(4):539-549. doi:10.1111/acer.12006*



Lifext — !



? ! :



  • , , ;
  • ;
  • ;
  • : ;
  • , ;( !)


— + .



, Google. Lifext, .



, , ;)










All Articles